Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced hypothalmic-pituitary-adrenal (HPA) axis suppression and Cushing's syndrome than mature patients because of a larger skin surface area to body weight ratio . HPA axis suppression, Cushing's syndrome, and intracranial hypertension have been reported in children receiving topical corticosteroids. Manifestations of adrenal suppression in children include linear growth retardation, delayed weight gain, low plasma cortisol levels, and absence of response to ACTH stimulation. Manifestations of intracranial hypertension include bulging fontanelles, headaches, and bilateral papilledema.
I cannot express my heartbreak for you and the loss of your precious daughter. I have 2 and a granddaughter. They are my life as well as my wife. I can’t help but feel a negligence on the part of the medical staff, in my opinion. Your daughter was off the opiates for awhile making her ‘opiate naive’. That amount of medication,dosage,etc. would definitely kill someone especially if there’s no home are staff or med staff around to monitor the situation.
Please accept my deepest and sincerest of sympathies and if you don’t mind, I’ll keep you in my prayers.